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Kim-Anh Le Cao
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CellDiffusion: a generative model to annotate single-cell and spatial RNA-seq using bulk references
We introduce the first manuscript of our PhD student Xiaochen Zhang! CellDiffusion bridges the gap between single-cell, spatial and bulk RNA-seq, using a diffusion-based generative model to create virtual cells that mimic the gene expression profiles …
lecao-lab.science.unimelb.edu.au/2025/10/30/celldiffusion-a-generative-model-to-annotate-single-cell-and-spatial-rna-seq-using-bulk-references
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NeighbourNet: Scalable cell-specific co-expression networks for granular regulatory pattern discovery
We introduce the latest work from our PhD student Yidi Deng (who has already secured a postdoc position at ANU!). Understanding how genes interact at the …
lecao-lab.science.unimelb.edu.au/2025/04/04/neighbournet
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Φ-Space ST: a platform-agnostic method to identify cell states in spatial transcriptomics studies + seminar recording
Dr Jiadong Mao has worked on an extension of his previous method Φ-Space for spatial transcriptomics studies! We are very excited about these new developments and …
lecao-lab.science.unimelb.edu.au/2025/02/12/%cf%86-space-st
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mixOmics online workshop starts 24th Feb, registrations are open
Registrations for our next online course are now open! Registration and details: https://mixomics.org/2024/12/online-course-feb-24-april-11-2025/ This course is designed for: Beginners looking for an introduction to mixOmics …
lecao-lab.science.unimelb.edu.au/2025/01/20/mixomics-online-workshop-starts-24th-feb-registrations-are-open
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Semisynthetic Simulation for Microbiome Data Analysis
Dr Kris Sankaran (University of Wisconsin) was one of our Belz recipient from the School of Maths & Stats and came for 6-week visit to our …
lecao-lab.science.unimelb.edu.au/2025/01/20/semisynthetic-simulation-microbiome
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Gene Content of Seawater Microbes is a Strong Predictor of Water Chemistry Across the Great Barrier Reef
PhD candidate Marko Terzin from James Cook University and the Australian Institute of Marine Science (AIMS) has spent a few months in 2023 in our lab …
lecao-lab.science.unimelb.edu.au/2025/01/03/gene-microbes-predictors-grf
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Global picoplankton biogeography revealed by metagenomic and climatic data integration
Vini Salazar is reaching the end of his PhD candidature (and has already secured a continuing position at Melbourne Bioinformatics, UoM 🎉). His preprint is one …
lecao-lab.science.unimelb.edu.au/2025/01/02/global-picoplankton-biogeography-revealed-by-metagenomic-and-climatic-data-integration
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PLSKO: a robust knockoff generator to control false discovery rate in omics variable selection
Our PhD student Guannan Yang has submitted her first manuscript! PLSKO is a new and robust knockoff variable generator that is applicable to various types of …
lecao-lab.science.unimelb.edu.au/2024/08/15/plsko
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Φ-Space: Continuous phenotyping of single-cell multi-omics data with video!
Jiadong Mao has developed a new PLS method for cell type continuous annotation of single cells, now published in Genome Biology! Φ-Space addresses numerous challenges faced …
lecao-lab.science.unimelb.edu.au/2024/07/03/%cf%86-space
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Microbial network inference for longitudinal microbiome studies with LUPINE with video!
Dr Saritha Kodikara has developed a PLS-based to infer microbial networks across time! LUPINE is a PLS-based method that combines dimension reduction, and partial correlations to …
lecao-lab.science.unimelb.edu.au/2024/05/17/lupine
Number of posts found: 63